Concepts and Design of Materials Nanoarchitectonics
CHAPTER 17: Design of Nanostructured Lipid Carriers and Hybrid Lipid Nanoparticles
Published:09 Feb 2022
I. R. Berti, T. Singh, T. Boztepe, I. E. Leon, A. K. Nadda, and G. R. Castro, in Concepts and Design of Materials Nanoarchitectonics, ed. O. Azzaroni and K. Ariga, The Royal Society of Chemistry, 2022, pp. 381-416.
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Nanoparticles composed of solid lipids and their hybrid formulations containing polymers, peptides, proteins, and inorganic compounds are valuable materials for the future development of therapeutic devices. Hybrid lipid carriers are multipurpose, and they can be formulated for the delivery of hydrophobic as well as hydrophilic drugs. Among their main advantages are high payload and stability, established controlled release kinetics, easy targeting, simple production and scale-up, a wide range of administration routes.