Skip Nav Destination
Drug Discovery
New Tools to Interrogate Endocannabinoid Signalling: From Natural Compounds to Synthetic Drugs
Edited by
Mauro Maccarrone
Mauro Maccarrone
University of Rome, Italy
Search for other works by this author on:
Hardback ISBN:
978-1-78801-801-2
PDF ISBN:
978-1-83916-075-2
EPUB ISBN:
978-1-83916-085-1
Special Collection:
2020 ebook collection
Series:
Drug Discovery
No. of Pages:
458
Published online:
06 Nov 2020
Published in print:
16 Nov 2020
About this book
Legalization of cannabis extracts around the world has led to a resurgence of interest into research surrounding endocannabinoids (eCBs) and the endocannabinoid system. This system is formed of a complex array of receptors, metabolic enzymes and transporters that finely tune the manifold biological activities of eCBs and there is an urgent need for the development of selective drugs to dissect the contribution of eCBs to the aetiology of various diseases. New Tools to Interrogate Endocannabinoid Signalling comprehensively covers the innovative research into both natural and synthetic compounds that affect this pathway and taking a target-based approach, assesses their potential for therapeutic use. With contributions from global leaders in the field, this timely volume will be a valuable resource to pharmaceutical researchers and medicinal chemists working in natural products and endocannabinoid drug discovery in academia and industry.
New Tools to Interrogate Endocannabinoid Signalling: From Natural Compounds to Synthetic Drugs, The Royal Society of Chemistry, 2020.
Download citation file:
Digital access
$220.00
Print format
New Tools to Interrogate Endocannabinoid Signalling
$220.00
Table of contents
-
Chapter 1: Quest for Magic Bullets to Solve the Endocannabinoid Puzzlep1-9ByMauro MaccarroneMauro MaccarroneDepartment of Applied Clinical and Biotechnological SciencesUniversity of L'AquilaI-67100 L'AquilaItaly[email protected]European Center for Brain Research, IRCCS Santa Lucia FoundationVia del Fosso di Fiorano 64I-00143 RomeItalySearch for other works by this author on:
-
Chapter 2: Phytocannabinoids Versus Endocannabinoids. A Modern View of the Endocannabinoid Systemp10-47ByJavier Fernández-Ruiz;Javier Fernández-RuizInstituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad ComplutenseMadridSpain[email protected]J.Ferná[email protected]Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos IIIMadridSpainInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS)MadridSpainSearch for other works by this author on:Onintza Sagredo;Onintza SagredoInstituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad ComplutenseMadridSpain[email protected]J.Ferná[email protected]Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos IIIMadridSpainInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS)MadridSpainSearch for other works by this author on:Eva de LagoEva de LagoInstituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad ComplutenseMadridSpain[email protected]J.Ferná[email protected]Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos IIIMadridSpainInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS)MadridSpainSearch for other works by this author on:
-
Chapter 3: Natural Compounds and Synthetic Drugs to Target Type-1 Cannabinoid (CB1) Receptorp48-88ByChristos Iliopoulos-Tsoutsouvas;Christos Iliopoulos-TsoutsouvasNortheastern University, Center for Drug Discovery and Department of Pharmaceutical Sciences360 Huntington AvenueBostonMassachusetts 02115USA[email protected][email protected]Search for other works by this author on:Markos-Orestis Georgiadis;Markos-Orestis GeorgiadisNortheastern University, Center for Drug Discovery and Department of Pharmaceutical Sciences360 Huntington AvenueBostonMassachusetts 02115USA[email protected][email protected]Search for other works by this author on:Lipin Ji;Lipin JiNortheastern University, Center for Drug Discovery and Department of Pharmaceutical Sciences360 Huntington AvenueBostonMassachusetts 02115USA[email protected][email protected]Search for other works by this author on:Spyros P. Nikas;Spyros P. NikasNortheastern University, Center for Drug Discovery and Department of Pharmaceutical Sciences360 Huntington AvenueBostonMassachusetts 02115USA[email protected][email protected]Search for other works by this author on:Alexandros MakriyannisAlexandros MakriyannisNortheastern University, Center for Drug Discovery and Department of Pharmaceutical Sciences360 Huntington AvenueBostonMassachusetts 02115USA[email protected][email protected]Northeastern University, Department of Chemistry and Chemical Biology360 Huntington AvenueBostonMassachusetts 02115USASearch for other works by this author on:
-
Chapter 4: Natural Compounds and Synthetic Drugs to Target Type-2 Cannabinoid (CB2) Receptorp89-167ByWolfgang Guba;Wolfgang GubaRoche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd.4070 BaselSwitzerland[email protected]Search for other works by this author on:Marc Nazaré;Marc NazaréLeibniz-Forschungsinstitut für Molekulare Pharmakologie FMP, Campus Berlin-Buch13125 BerlinGermany[email protected]Search for other works by this author on:Uwe GretherUwe GretherRoche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd.4070 BaselSwitzerland[email protected]Search for other works by this author on:
-
Chapter 5: Natural and Synthetic Cannabinoids Targeting Non-CB1, Non-CB2 G Protein-coupled Receptorsp168-200ByPaula Morales;Paula MoralesInstituto de Química Medica (IQM-CSIC)C/Juan de la Cierva 3Madrid28006SpainSearch for other works by this author on:Israa H. Isawi;Israa H. IsawiDepartment of Chemistry and Biochemistry, University of North Carolina at GreensboroGreensboroNC 27412USA[email protected]Search for other works by this author on:Patricia H. ReggioPatricia H. ReggioDepartment of Chemistry and Biochemistry, University of North Carolina at GreensboroGreensboroNC 27412USA[email protected]Search for other works by this author on:
-
Chapter 6: Natural Compounds and Synthetic Drugs Targeting the Ionotropic Cannabinoid Members of Transient Receptor Potential (TRP) Channelsp201-300ByRosa Maria Vitale;Rosa Maria VitaleInstitute of Biomolecular Chemistry (ICB)-National Research Council (CNR)Via Campi Flegrei 3480078 Pozzuoli (NA)Italy[email protected][email protected]Search for other works by this author on:Aniello Schiano Moriello;Aniello Schiano MorielloEpitech Group SpASaccolongo, PadovaItalyEndocannabinoid Research Group - Institute of Biomolecular Chemistry (ICB)-National Research Council (CNR)Via Campi Flegrei 3480078 Pozzuoli (NA)ItalySearch for other works by this author on:Luciano De PetrocellisLuciano De PetrocellisInstitute of Biomolecular Chemistry (ICB)-National Research Council (CNR)Via Campi Flegrei 3480078 Pozzuoli (NA)Italy[email protected][email protected]Endocannabinoid Research Group - Institute of Biomolecular Chemistry (ICB)-National Research Council (CNR)Via Campi Flegrei 3480078 Pozzuoli (NA)ItalySearch for other works by this author on:
-
Chapter 7: Inhibition of NAPE-PLD Activity by Natural Compounds and Synthetic Drugs, and Its Biological Relevancep301-336ByK. Tsuboi;K. TsuboiKawasaki Medical School, Department of Pharmacology577 MatsushimaKurashikiOkayama 701-0192JapanKagawa University School of Medicine, Department of Biochemistry1750-1 IkenobeMikiKagawa 761-0793Japan[email protected]Search for other works by this author on:T. Uyama;T. UyamaKagawa University School of Medicine, Department of Biochemistry1750-1 IkenobeMikiKagawa 761-0793Japan[email protected]Search for other works by this author on:N. UedaN. UedaKagawa University School of Medicine, Department of Biochemistry1750-1 IkenobeMikiKagawa 761-0793Japan[email protected]Search for other works by this author on:
-
Chapter 8: Natural Compounds and Synthetic Drugs to Target FAAH Enzymep337-384ByS. Butini;S. ButiniUniversity of Siena, Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018–2022via Aldo Moro 2I-53100 SienaItaly[email protected]Search for other works by this author on:S. Gemma;S. GemmaUniversity of Siena, Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018–2022via Aldo Moro 2I-53100 SienaItaly[email protected]Search for other works by this author on:G. CampianiG. CampianiUniversity of Siena, Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018–2022via Aldo Moro 2I-53100 SienaItaly[email protected]Search for other works by this author on:
-
Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activityp385-413ByLaura Scalvini;Laura ScalviniDepartment of Food and Drug, University of ParmaParco Area delle Scienze 27/AI-43124 ParmaItaly[email protected]Search for other works by this author on:Silvia Rivara;Silvia RivaraDepartment of Food and Drug, University of ParmaParco Area delle Scienze 27/AI-43124 ParmaItaly[email protected]Search for other works by this author on:Kwang-Mook Jung;Kwang-Mook JungDepartment of Anatomy and Neurobiology, School of Medicine, Departments of Biological Chemistry and Pharmacology, School of Medicine and Center for the Study of Cannabis, University of CaliforniaIrvineCalifornia 92697USA[email protected]Search for other works by this author on:Marco Mor;Marco MorDepartment of Food and Drug, University of ParmaParco Area delle Scienze 27/AI-43124 ParmaItaly[email protected]Search for other works by this author on:Daniele PiomelliDaniele PiomelliDepartment of Anatomy and Neurobiology, School of Medicine, Departments of Biological Chemistry and Pharmacology, School of Medicine and Center for the Study of Cannabis, University of CaliforniaIrvineCalifornia 92697USA[email protected]Search for other works by this author on:
-
Chapter 10: Small-molecule Inhibitors of Endocannabinoid Transport and Traffickingp414-450ByInés Reynoso Moreno;Inés Reynoso MorenoInstitute of Biochemistry and Molecular Medicine, NCCR TransCure, University of BernSwitzerland[email protected]Search for other works by this author on:Jürg GertschJürg GertschInstitute of Biochemistry and Molecular Medicine, NCCR TransCure, University of BernSwitzerland[email protected]Search for other works by this author on:
Spotlight
Advertisement
Advertisement
