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Biomaterials Science Series
Extracellular Vesicles: Applications to Regenerative Medicine, Therapeutics and Diagnostics
Edited by
Wojciech Chrzanowski;
Wojciech Chrzanowski
University of Sydney, Australia
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Chwee Teck Lim;
Chwee Teck Lim
National University of Singapore, Singapore
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Sally Yunsun Kim
Sally Yunsun Kim
Imperial College London, UK
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Hardback ISBN:
978-1-78801-894-4
PDF ISBN:
978-1-83916-455-2
EPUB ISBN:
978-1-83916-456-9
Special Collection:
2021 ebook collection
Series:
Biomaterials Science Series
No. of Pages:
344
Publication date:
20 Oct 2021
About this book
Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field.
Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The reader will then learn about the isolation of extracellular vesicles their physicochemical characterisation and therapeutic application of EVs in regenerative medicine as well as their potential as biomarkers in medical diagnostic. This book will also discuss the regulatory landscape of EVs.
Bridging cell biology, biomaterials, biophysics and biomedical engineering the content of this book is written with a broad interdisciplinary audience in mind. Researchers, new and established will find this a must-have on their shelf.
Extracellular Vesicles: Applications to Regenerative Medicine, Therapeutics and Diagnostics, The Royal Society of Chemistry, 2021.
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Digital access
$235.00
Print format
Extracellular Vesicles
$235.00
Table of contents
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CHAPTER 1: Therapeutic Potential of Mesenchymal Stromal Cell-derived Small Extracellular Vesiclesp1-21ByFabiola Nardi Bauer;Fabiola Nardi BauerInstitute for Transfusion Medicine, University Hospital EssenVirchowstraβe 17945147 EssenGermany[email protected]Search for other works by this author on:Bernd GiebelBernd GiebelInstitute for Transfusion Medicine, University Hospital EssenVirchowstraβe 17945147 EssenGermany[email protected]Search for other works by this author on:
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CHAPTER 2: Separation and Purification of Extracellular and Bio-fluid Vesicles – State of the Art: Past, Present, and Future of Extracellular Vesicle Separation and Purificationp22-44ByVijaya Sunkara;Vijaya SunkaraCenter for Soft and Living Matter, Institute for Basic Science (IBS)Ulsan 44919Republic of Korea[email protected]Search for other works by this author on:Hyun-Kyung Woo;Hyun-Kyung WooCenter for Soft and Living Matter, Institute for Basic Science (IBS)Ulsan 44919Republic of Korea[email protected]Search for other works by this author on:Yoon-Kyoung ChoYoon-Kyoung ChoCenter for Soft and Living Matter, Institute for Basic Science (IBS)Ulsan 44919Republic of Korea[email protected]Department of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST)Ulsan 44919Republic of KoreaSearch for other works by this author on:
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CHAPTER 3: Physicochemical Characterisation of Extracellular Vesiclesp45-75BySu Hyeon Park;Su Hyeon ParkThe University of Sydney, Faculty of Medicine and Health, Sydney School of PharmacyPharmacy and Bank Building A15CamperdownNSW 2006AustraliaSearch for other works by this author on:Thanh Huyen Phan;Thanh Huyen PhanThe University of Sydney, Sydney Nano Institute, Faculty of Medicine and Health, Sydney School of PharmacyPharmacy and Bank Building A15CamperdownNSW 2006Australia[email protected]Search for other works by this author on:Jeung Eun Kim;Jeung Eun KimUniversity of New South Wales, Faculty of Business, School of Risk and Actuarial Studies, UNSW Business School BuildingUNSW SydneyNSW 2052AustraliaSearch for other works by this author on:Wojciech ChrzanowskiWojciech ChrzanowskiThe University of Sydney, Sydney Nano Institute, Faculty of Medicine and Health, Sydney School of PharmacyPharmacy and Bank Building A15CamperdownNSW 2006Australia[email protected]Search for other works by this author on:
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CHAPTER 4: Biological Characterization of Extracellular Vesicles – Methodologies to Characterize Molecular Composition of Extracellular Vesicles – Advances Towards Single Vesicle Characterizationp76-94ByKirsi RillaKirsi RillaInstitute of Biomedicine, School of Medicine, University of Eastern FinlandYliopistonranta 1E70211 KuopioFinland[email protected]Search for other works by this author on:
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CHAPTER 5: Extracellular Vesicles in Bone Tissue Engineeringp95-137ByOwen G. DaviesOwen G. DaviesSchool of Sport, Exercise and Health Sciences, Loughborough UniversityEpinal WayLoughboroughLeicestershireLE11 3TUUK[email protected]Search for other works by this author on:
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CHAPTER 6: Mesenchymal Stromal Cell (MSC)-derived Small Extracellular Vesicles as Next-generation Therapeutics for Cartilage Regenerationp138-160ByWei Seong TohWei Seong TohDepartment of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of SingaporeSingaporeDepartment of Biomedical Engineering, Faculty of Engineering, National University of SingaporeSingaporeTissue Engineering Program, Life Sciences Institute, National University of SingaporeSingaporeGraduate School for Integrative Sciences and Engineering, National University of SingaporeSingaporeSearch for other works by this author on:
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CHAPTER 7: The Role of Extracellular Vesicles in the Neuronal System: Application of Extracellular Vesicles in Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, and Dementiap161-189ByK. GroenK. GroenSchool of Biomedical Sciences and Pharmacy, University of NewcastleCallaghan NSW 2308Australia[email protected]Centre for Brain and Mental Health Research, Hunter Medical Research InstituteNew Lambton Heights NSW 2305AustraliaSearch for other works by this author on:
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CHAPTER 8: The Role of Extracellular Vesicles in Aging of the Human Placentap190-215ByS. Zheng;S. ZhengPregnancy Research Centre, Department of Maternal-Fetal Medicine, Royal Women's HospitalParkvilleVIC3052AustraliaUniversity of Melbourne Department of Obstetrics and Gynaecology, Royal Women's HospitalParkvilleVIC3052Australia[email protected]Search for other works by this author on:J. C. Wijaya;J. C. WijayaPregnancy Research Centre, Department of Maternal-Fetal Medicine, Royal Women's HospitalParkvilleVIC3052AustraliaUniversity of Melbourne Department of Obstetrics and Gynaecology, Royal Women's HospitalParkvilleVIC3052Australia[email protected]Search for other works by this author on:R. Khanabdali;R. KhanabdaliExopharm LimitedLevel 17/31 Queen StMelbourneVIC3000AustraliaSearch for other works by this author on:M. I. Kokkinos;M. I. KokkinosPregnancy Research Centre, Department of Maternal-Fetal Medicine, Royal Women's HospitalParkvilleVIC3052AustraliaSearch for other works by this author on:B. KalionisB. KalionisPregnancy Research Centre, Department of Maternal-Fetal Medicine, Royal Women's HospitalParkvilleVIC3052AustraliaUniversity of Melbourne Department of Obstetrics and Gynaecology, Royal Women's HospitalParkvilleVIC3052Australia[email protected]Search for other works by this author on:
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CHAPTER 9: Extracellular Vesicles in Lung Diseasesp216-245ByS. Bayer;S. BayerDepartment of Obstetrics and Gynaecology, Monash UniversityClaytonVICAustraliaThe Ritchie Centre, Hudson Institute of Medical ResearchClaytonVICAustraliaSearch for other works by this author on:D. Zhu;D. ZhuDepartment of Obstetrics and Gynaecology, Monash UniversityClaytonVICAustraliaThe Ritchie Centre, Hudson Institute of Medical ResearchClaytonVICAustraliaSearch for other works by this author on:R. Lim;R. LimDepartment of Obstetrics and Gynaecology, Monash UniversityClaytonVICAustraliaThe Ritchie Centre, Hudson Institute of Medical ResearchClaytonVICAustraliaSearch for other works by this author on:M. Hind;M. HindNational Institute for Health Research (NIHR) Respiratory Biomedical Research Unit at the Royal Brompton & Harefield NHS Foundation Trust and Imperial CollegeLondonUKSearch for other works by this author on:M. Griffiths;M. GriffithsPeri-Operative Medicine, St Bartholomew's HospitalLondonUKSearch for other works by this author on:C. H. Dean;C. H. DeanMRC Harwell Institute, Harwell CampusOxfordshireUKSearch for other works by this author on:S. Y. KimS. Y. KimSearch for other works by this author on:
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CHAPTER 10: Immunomodulatory Function of Extracellular Vesicles in Cancer and Tissue Repair/Regenerationp246-270ByS. G. Santos;S. G. Santosi3S - Instituto de Investigação e Inovação em Saúde, and INEB - Instituto de Engenharia Biomédica, Universidade do PortoRua Alfredo Allen 2084200-135 PortoPortugal[email protected]ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do PortoR. Jorge de Viterbo Ferreira 2284050-313 PortoPortugalSearch for other works by this author on:R. M. Gonçalves;R. M. Gonçalvesi3S - Instituto de Investigação e Inovação em Saúde, and INEB - Instituto de Engenharia Biomédica, Universidade do PortoRua Alfredo Allen 2084200-135 PortoPortugal[email protected]ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do PortoR. Jorge de Viterbo Ferreira 2284050-313 PortoPortugalSearch for other works by this author on:J. Caldeira;J. Caldeirai3S - Instituto de Investigação e Inovação em Saúde, and INEB - Instituto de Engenharia Biomédica, Universidade do PortoRua Alfredo Allen 2084200-135 PortoPortugal[email protected]Search for other works by this author on:M. A. Barbosa;M. A. Barbosai3S - Instituto de Investigação e Inovação em Saúde, and INEB - Instituto de Engenharia Biomédica, Universidade do PortoRua Alfredo Allen 2084200-135 PortoPortugal[email protected]ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do PortoR. Jorge de Viterbo Ferreira 2284050-313 PortoPortugalSearch for other works by this author on:M. J. OliveiraM. J. Oliveirai3S - Instituto de Investigação e Inovação em Saúde, and INEB - Instituto de Engenharia Biomédica, Universidade do PortoRua Alfredo Allen 2084200-135 PortoPortugal[email protected]ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do PortoR. Jorge de Viterbo Ferreira 2284050-313 PortoPortugalDepartamento de Patologia e Oncologia, Faculdade de Medicina, Universidade do PortoAlameda Prof. Hernâni Monteiro4200-319PortoPortugalSearch for other works by this author on:
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CHAPTER 11: Diagnostic Applications of Extracellular and Bio-fluid Vesiclesp271-302ByChi Yan Wong;Chi Yan WongInstitute for Health Innovation & Technology, National University of Singapore117599Singapore[email protected]Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore119228SingaporeSearch for other works by this author on:Li Zhang;Li ZhangInstitute for Health Innovation & Technology, National University of Singapore117599Singapore[email protected]Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore117583SingaporeSearch for other works by this author on:Huilin ShaoHuilin ShaoInstitute for Health Innovation & Technology, National University of Singapore117599Singapore[email protected]Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore117583SingaporeDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore117597SingaporeInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research138673SingaporeNational Neuroscience Institute308433SingaporeSearch for other works by this author on:
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CHAPTER 12: Standardization and Commercialization of Extracellular Vesiclesp303-335ByR. Zenatelli;R. ZenatelliDepartment of Molecular and Translational Medicine, University of BresciaBresciaItalySearch for other works by this author on:L. Paolini;L. PaoliniDepartment of Molecular and Translational Medicine, University of BresciaBresciaItalyCSGI, Italian Center for Colloid and Interface ScienceFlorenceItalySearch for other works by this author on:G. Adamo;G. AdamoInstitute for Research and Biomedical Innovation (IRIB), National Research CouncilPalermoItalySearch for other works by this author on:A. Radeghieri;A. RadeghieriDepartment of Molecular and Translational Medicine, University of BresciaBresciaItalyCSGI, Italian Center for Colloid and Interface ScienceFlorenceItalySearch for other works by this author on:A. Bongiovanni;A. BongiovanniInstitute for Research and Biomedical Innovation (IRIB), National Research CouncilPalermoItalySearch for other works by this author on:P. BergeseP. BergeseDepartment of Molecular and Translational Medicine, University of BresciaBresciaItalyCSGI, Italian Center for Colloid and Interface ScienceFlorenceItalyInstitute for Research and Biomedical Innovation (IRIB), National Research CouncilPalermoItalySearch for other works by this author on:
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