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New Developments in Mass Spectrometry
MALDI Mass Spectrometry Imaging: From Fundamentals to Spatial Omics
Edited by
Tiffany Porta Siegel
Tiffany Porta Siegel
Maastricht University, The Netherlands
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Hardback ISBN:
978-1-83916-241-1
PDF ISBN:
978-1-83916-519-1
EPUB ISBN:
978-1-83916-520-7
Special Collection:
2021 ebook collection
No. of Pages:
500
Publication date:
23 Nov 2021
About this book
This book gathers, in a single resource, knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging. It includes fundamentals in the MALDI ionisation process, different source geometries and capabilities, detection systems and the latest research and applications in the range of –omics area as well as other broader areas. Chapters will touch on dedicated sample preparation protocols specific for the class of compounds of interest, instrumentation used with strengths and current limitations, strategies for structural analysis and identification and applications. It will be a welcomed addition to the literature in this fast-moving field and provide a guide to new innovations and applications especially in metabolomics and proteomics.
With contributions from leading experts, this book will be an authoritative guide to this method. Aimed at postgraduate and professional researchers, in academia and in the industrial market where it has direct application to clinical research. It will be a supporting volume for those just entering the field as well as experienced practitioners.
MALDI Mass Spectrometry Imaging: From Fundamentals to Spatial Omics, The Royal Society of Chemistry, 2021.
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Digital access
$250.00
Print format
MALDI Mass Spectrometry Imaging
$250.00
Table of contents
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Chapter 1: An Introduction to MALDI Ionization Mechanisms for Users of Mass Spectrometry Imagingp1-19ByRichard KnochenmussRichard KnochenmussSearch for other works by this author on:
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Chapter 2: MALDI Mass Spectrometry Imaging – Past, Present, and Future Challengesp20-38ByPierre ChaurandPierre ChaurandSearch for other works by this author on:
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Chapter 3: Instrumentation for MALDI-MSI – Part I Ionization Sources and Designp39-58ByJens SoltwischJens SoltwischSearch for other works by this author on:
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Chapter 4: Instrumentation for MALDI-MSI – Part II Detection Systemsp59-86ByBoone M. Prentice;Boone M. PrenticeDepartment of Chemistry, University of FloridaGainesvilleFlorida 32611USASearch for other works by this author on:Jeffrey M. SpragginsJeffrey M. SpragginsDepartment of Cell and Developmental Biology and Mass Spectrometry Research Center, Vanderbilt University School of MedicineNashvilleTennessee 37240USA[email protected]Search for other works by this author on:
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Chapter 5: Sample Preparation of Biological Tissues for MALDI-MSIp87-104ByBerta Cillero-Pastor;Berta Cillero-PastorDivision of Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging (M4i) Institute6229 ER MaastrichtNetherlands[email protected]Search for other works by this author on:Eva CuypersEva CuypersDivision of Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging (M4i) Institute6229 ER MaastrichtNetherlands[email protected]Search for other works by this author on:
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Chapter 6: Quantitative MSI: A Review of Biomarker and Drug Quantifications Using Mass Spectrometry Imagingp105-130ByJonathan StauberJonathan StauberSearch for other works by this author on:
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Chapter 7: MALDI Mass Spectrometry Imaging and Metabolomics – A Glimpse into the Local Metabolic State of Cells and Tissuesp131-156ByHannah Bednarz;Hannah BednarzBielefeld University, Medical School OWL, Sustainable Environmental Health Sciences33615BielefeldGermanySearch for other works by this author on:Karsten NiehausKarsten NiehausBielefeld University, Proteome and Metabolome Research, Center for Biotechnology (CeBiTec) & Faculty of Biology33615BielefeldGermany[email protected]Search for other works by this author on:
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Chapter 8: MALDI Mass Spectrometry Imaging in Lipidomicsp157-187ByShadrack M. Mutuku;Shadrack M. MutukuMolecular Horizons and School of Chemistry and Molecular Bioscience, University of WollongongWollongongNSWAustralia[email protected]Search for other works by this author on:Shane R. EllisShane R. EllisMolecular Horizons and School of Chemistry and Molecular Bioscience, University of WollongongWollongongNSWAustralia[email protected]Illawarra Health and Medical Research InstituteWollongongNSWAustraliaSearch for other works by this author on:
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Chapter 9: MALDI Mass Spectrometry Imaging of Neuropeptidesp188-206ByJörg HanriederJörg HanriederDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy at the University of GothenburgMölndal Hospital, SE-431 80 MölndalSweden[email protected]Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, Queen SquareLondon WC1N 3BGUnited KingdomSearch for other works by this author on:
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Chapter 10: MALDI Mass Spectrometry Imaging and Glycomicsp207-233ByCalvin R. K. Blaschke;Calvin R. K. BlaschkeDepartment of Cell and Molecular Pharmacology, Medical University of South Carolina173 Ashley AvenueCharleston29425 South CarolinaUnited States[email protected]Search for other works by this author on:Richard R. DrakeRichard R. DrakeDepartment of Cell and Molecular Pharmacology, Medical University of South Carolina173 Ashley AvenueCharleston29425 South CarolinaUnited States[email protected]Search for other works by this author on:
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Chapter 11: MALDI Mass Spectrometry Imaging and Spatially-resolved Proteomicsp234-261ByEduardo Chicano-Galvez;Eduardo Chicano-GalvezIMIBIC Mass Spectrometry and Molecular Imaging Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba (UCO)CórdobaSpain[email protected]Search for other works by this author on:Michel Salzet;Michel SalzetUniv. Lille, Inserm, CHU Lille, U1192 - Protéomique Réponse Inflammatoire Spectrométrie de Masse - PRISMF-59000 LilleFrance[email protected]Institut Universitaire de France (IUF)ParisFranceSearch for other works by this author on:ISABELLE FournierISABELLE FournierUniv. Lille, Inserm, CHU Lille, U1192 - Protéomique Réponse Inflammatoire Spectrométrie de Masse - PRISMF-59000 LilleFrance[email protected]Institut Universitaire de France (IUF)ParisFranceSearch for other works by this author on:
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Chapter 12: The Role of Informatics and Data Analysis in MALDI Mass Spectrometry Imagingp262-290ByBENJAMIN BalluffBENJAMIN BalluffMaastricht MultiModal Molecular Imaging Institute (M4i), Maastricht University6229 ER MaastrichtThe Netherlands[email protected]Search for other works by this author on:
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Chapter 13: MALDI Mass Spectrometry Imaging for Microbiologyp291-320ByLaura M. SanchezLaura M. SanchezSearch for other works by this author on:
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Chapter 14: MALDI Mass Spectrometry Imaging in Drug Discovery and Developmentp321-358ByPeter S. Marshall;Peter S. MarshallGlaxoSmithKlineStevenageUKSearch for other works by this author on:M. Reid GrosecloseM. Reid GrosecloseSearch for other works by this author on:
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Chapter 15: MALDI Mass Spectrometry Imaging in the Forensic Arenap359-386ByRobert Bradshaw;Robert BradshawBiomolecular Sciences Research Centre (BMRC), Sheffield Hallam UniversitySheffieldUK[email protected]Search for other works by this author on:Simona FranceseSimona FranceseBiomolecular Sciences Research Centre (BMRC), Sheffield Hallam UniversitySheffieldUK[email protected]Search for other works by this author on:
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Chapter 16: MALDI Mass Spectrometry Imaging for Toxicological Evaluation of Environmental Pollutantsp387-407ByMélanie Lagarrigue;Mélanie LagarrigueUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)UMR_S 1085Rennes CedexF-35042FranceSearch for other works by this author on:Mira Merdas;Mira MerdasUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)UMR_S 1085Rennes CedexF-35042FranceTechnologie Servier25/27 rue Eugène Vignat – CS 1174945007 Orléans Cedex 1FranceSearch for other works by this author on:Charles PineauCharles PineauUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)UMR_S 1085Rennes CedexF-35042FranceSearch for other works by this author on:
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Chapter 17: MALDI Mass Spectrometry Imaging in the Clinical Landscapep408-431ByKristina SchwambornKristina SchwambornSearch for other works by this author on:
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Chapter 18: MALDI Mass Spectometry Imaging for Eye Diseasesp432-456ByKevin L. ScheyKevin L. ScheyDepartment of Biochemistry, Vanderbilt UniversityUSASearch for other works by this author on:
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Chapter 19: Correlative Multimodal Mass Spectometry Imaging – Imaging Across the Scalesp457-476ByMartina Marchetti-DeschmannMartina Marchetti-DeschmannInstitute of Chemical Technologies and Analytics, TU WienGetreidemarkt 9/1641060 ViennaAustria[email protected]Search for other works by this author on:
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