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The treatment of industrial effluent is significant for the protection of both ecology and human health. Various technologies have been developed for the treatment of industrial effluent. Among these technologies, the biological treatment process is one of them. Despite their longer operating times, biological therapies are cost-effective compared to other treatment methods. Thus, special attention should be given to the design of different advanced bioreactors, the shortcomings of those bioprocesses, and their performance characteristics. Advanced bioreactors include models such as the sequencing batch biofilm reactor, stirred tank bioreactor to packed bed, moving bed, fluidized, semi-fluidized and inverse fluidized bed, sludge bed and downflow fixed bed/film bioreactors. Sometimes, membrane-based technology can also be used with these designs. This chapter discusses the different systems of advanced bioreactors, mainly sequencing batch, aerobic and anaerobic stirred tank, fixed and fluidized bed reactors. The discussion has also been extended to the use of the membrane technology with bioreactor designs and all possible integrated approaches for improving the process efficiency.

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