The Coronavirus Pandemic and the Future Volume 2
CHAPTER 6: The Potential Therapeutic Effects of Natural Products, Herbs, and Mushrooms Against COVID-19
Published:27 Apr 2022
M. Najafzadeh, F. Shahzad, and D. Anderson, in The Coronavirus Pandemic and the Future Volume 2, ed. M. D. Waters, A. Dhawan, T. Marrs, D. Anderson, S. Warren, C. L. Hughes, ... C. L. Hughes, The Royal Society of Chemistry, 2022, pp. 177-196.
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An acute respiratory disease caused by the 2019 novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), otherwise known as coronavirus disease 2019 (COVID-19), recently emerged in Wuhan, Hubei Province, China, and has since spread rapidly across the globe. As of 30 January 2020, the COVID-19 epidemic was officially declared as a public health emergency of international concern by the World Health Organization (WHO). Coronaviruses are enveloped positive-sense RNA viruses that can cause a variety of diseases in both birds and mammals. SARS-CoV-2 is a novel strain that has not been previously identified in humans. However, it is the third introduction of a highly pathogenic coronavirus into the human population since SARS-CoV-1 was identified in 2002 and Middle East respiratory syndrome (MERS-CoV), which was first identified in 2012. To date, no effective or specific treatment has been identified for SARS-CoV-2; despite this, certain candidates have shown great efficacy in viral inhibition of the disease. Natural substances have previously exhibited anti-viral and anti-inflammatory activity. Thus, the possibilities of natural substances as effective treatments against SARS-CoV-2 may seem promising. This chapter aims to provide a comprehensive overview of the possible use of natural products against SARS-CoV-2 by evaluating their anti-viral and anti-inflammatory effects, which have been assessed previously in laboratory conditions.