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Nanopores for Bioanalytical Applications: Proceedings of the International Conference
Edited by
Tim Albrecht
Tim Albrecht
University of Birmingham, UK
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Hardback ISBN:
978-1-84973-416-5
PDF ISBN:
978-1-84973-527-8
No. of Pages:
111
Published online:
05 Sep 2012
Published in print:
07 Sep 2012
Book Chapter
Improved Algorithms for Nanopore Signal Processing
By
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Published:05 Sep 2012
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Page range:
11 - 17
Citation
N. Arjmandi, W. Van Roy, L. Lagae, and G. Borghs, in Nanopores for Bioanalytical Applications: Proceedings of the International Conference, ed. J. Edel and T. Albrecht, The Royal Society of Chemistry, 2012, pp. 11-17.
Download citation file:
Nanopore signal processing generally consists of baseline removal, denoising, spike detection, extraction of spikes' amplitude and duration, and classification of spikes. Here we present an improved method for baseline removing, an optimized algorithm for denoising the nanopore signals, a novel method for spike detection that detects all the translocation spikes more correctly, and an improved and physically meaningful algorithm for measuring the duration and amplitude of the translocation spikes.
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