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Nanopores for Bioanalytical Applications: Proceedings of the International Conference
Edited by
Tim Albrecht
Tim Albrecht
University of Birmingham, UK
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Hardback ISBN:
978-1-84973-416-5
PDF ISBN:
978-1-84973-527-8
No. of Pages:
111
Published online:
05 Sep 2012
Published in print:
07 Sep 2012
Book Chapter
Salt and Voltage Dependence of the Conductance Blockade Induced by Translocation of DNA and RecA Filaments Through Solid-state Nanopores
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Published:05 Sep 2012
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Page range:
24 - 31
Citation
S. W. Kowalczyk and C. Dekker, in Nanopores for Bioanalytical Applications: Proceedings of the International Conference, ed. J. Edel and T. Albrecht, The Royal Society of Chemistry, 2012, pp. 24-31.
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Amongst many other applications, solid-state nanopores – tiny holes in a thin membrane – can be used for rapid single-molecule high-throughput label-free detection of small samples of, for example, DNA or DNA-protein complexes. The interpretation of the current signal that one observes when DNA transverses a nanopore is a central point in all nanopore work. However, a complete and thorough understanding is still lacking.
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