In this Part 3 of the book, we attempt to understand the impacts that chemical activity has on society and the environment. With the same application-oriented approach of the other two parts, we will focus on the role that chemical professionals play in the network of actors and decision-makers. Yet, first, it is necessary to show in which way chemistry is not per definition neutral or value-free. It is not difficult to see how the chemical industry, private sector research and design (R&D) and innovation, but also regulation and governance of chemical progress, have social and environmental implications that can be assessed and evaluated (thus, necessarily, implying values). For chemistry as an academic science and research it is not that obvious, though. Therefore, we will outline the ties between chemical science, technology development, innovation, and how progress is embedded in the social and cultural lifeworld of the people that it effects. Moreover, the chapter will introduce the contemporarily predominant social constructivist view of science and technology (S&T) progress by a short historical comparison with earlier paradigms. This will help us understand why reflecting on normative dimensions of scientific and innovation activity is not trivial or a waste of time, but an important element of research on how to make S&T progress sustainable and beneficial.