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The word ‘misuse’ as used in many Anglophone countries signifies the non-authorised use of medicines that can, in appropriate circumstances, be legally used. By contrast, The World Health Organization prefers the term ‘abuse’. Depending on the jurisdiction, the substances in question are referred to as either scheduled or controlled drugs. Overall drug use by adults in England and Wales has remained fairly stable in the past 20 years, although drug-associated fatal poisonings have reached an all-time high. The most commonly-used drug was cannabis (Class B) while around a third had taken a Class A drug. Apart from cannabis and amphetamine, use of other Class B drugs was much lower. Cocaine in any form, MDMA and ‘magic mushrooms’ were the most commonly-used Class A drugs. Most fatalities are associated with heroin and, to a lesser extent, with other narcotic analgesics. Drug seizures by law enforcement agencies are a less good measure of population use since they depend to a certain extent on the level of enforcement. They show a marked decline from the situation ten years ago. Nevertheless, in recent years, cannabis in its various forms has been the most commonly-seized drug, while cocaine including crack cocaine has been the most commonly-seized Class A drug. Despite their high political profile, new psychoactive substances represent a minor aspect of use, seizures and fatalities.

Drugs whose possession or supply is restricted by law are known as scheduled or, in the UK, as controlled substances. They comprise both licit materials (i.e., those manufactured under licence for clinical use) and the illicit products of clandestine factories. Although many plant-based drugs have been self-administered for thousands of years (e.g., coca leaf, cannabis, opium, and peyote cactus), the imposition of criminal sanctions is mostly a product of the 20th century. Many of the drugs currently misused were once not only on open sale, but often promoted as beneficial products by the food and pharmaceutical industries. A pattern developed whereby initial misuse of pharmaceutical products such as heroin, cocaine and amphetamine led to increasing legal restrictions and the consequent rise of an illicit industry.

The word ‘misuse’ signifies the non-authorised use of medicines that can, in appropriate circumstances, be legally used. That word has carried over into the title of the UK primary drug legislation, i.e., the Misuse of Drugs Act (MDAct), and to the corresponding legislation in a number of Anglophone countries. This was a departure from the earlier use in UK legislation of the title ‘Dangerous Drugs’. According to the WHO,1  scheduled drugs are ‘abused’. In this book, the term drug misuse is used since it is considered to be less judgemental. However, even the word ‘misuse’ is somewhat misleading since many controlled drugs are not and never have been used therapeutically. This is particularly true of the huge range of, mostly synthetic, psychoactive substances that have appeared in the past 30 years. In many cases, it is appropriate to say that such substances are merely ‘used’. It is equally correct to say that medicinal products both licit and illicit, such as the benzodiazepine tranquillisers and certain analgesic drugs, are ‘misused’. In the following text, and for convenience, the word ‘misuse’ applies to both situations.

Overall drug use in England and Wales has remained fairly stable in the past 20 years but is still predominantly associated with younger members of the population. Data for England and Wales are published, where appropriate, by the HO,2  the ONS,3  and the NHS.4  Separate arrangements operate in the devolved administrations in Scotland and Northern Ireland. To a certain extent many of these data collections are limited by various factors. Thus, household surveys can only reach those who live in normal circumstances; some problem drug users are homeless. Drug seizures also depend partly on the level of enforcement. Furthermore, the total quantity of drugs seized can be distorted in any period by unusually large seizures. For this reason, ‘number of seizures’ is a more reliable statistic, and particularly when relative seizures of closely related drugs are examined.

Figure 1.1 shows estimates of the numbers of illicit drug users (16- to 59-year-olds) in England and Wales2  in the period 2001/02 to 2017/18 for any drug broken down by those who have ‘ever taken in lifetime’ and ‘taken in the last year’. On both measures, the number of users has remained fairly stable in the period shown. About 20% of the adult population in England and Wales admits to having used a controlled drug at least once in their lives. Table 1.1 shows data for the same age group in 2017/2018 by drug type and when taken. The most common drug was cannabis while around a third had taken a Class A drug. Apart from cannabis and amphetamine, use of other Class B drugs was much lower. Cocaine in any form, ‘ecstasy’ (probably mostly MDMA) and ‘magic mushrooms’ were the most commonly-used Class A drugs. Heroin and other opiates were far less common. Despite the high level of public interest in new psychoactive substances (NPS), in 2017/2018 they represented only 7% of all users and, furthermore, apart from mephedrone, no data on NPS were collected before 2016. The final column in Table 1.1 gives an estimate of whether use of certain substances is declining/increasing relative to others. ‘Magic mushrooms’ and mephedrone show the lowest value of this index (i.e., greatest negative change) while cannabis, powder cocaine, ketamine and anabolic steroids show the highest values of the index (i.e., greatest increase).

Figure 1.1

Estimates of the numbers (thousands) of illicit drug users, 16- to 59-year-olds, in the period 2001/02 to 2017/18 (England and Wales) for any drug ‘ever taken in lifetime’ (black bars) and ‘taken in the last year’ (grey bars).

Figure 1.1

Estimates of the numbers (thousands) of illicit drug users, 16- to 59-year-olds, in the period 2001/02 to 2017/18 (England and Wales) for any drug ‘ever taken in lifetime’ (black bars) and ‘taken in the last year’ (grey bars).

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Table 1.1

Estimates of the numbers (thousands) of illicit drug users (16- to 59-year-olds) in 2017/2018 (England and Wales) by drug type and period when taken

SubstanceLast monthLast yearEverLast month/Ever
Powder cocaine 331 895 3576 0.09 
Crack cocaine 23 273 0.03 
Ecstasy 172 559 3386 0.05 
LSD 18 134 1755 0.01 
‘Magic mushrooms’ 10 142 2466 0.004 
Heroin 13 23 215 0.06 
Methadone 19 150 0.03 
Amphetamine 32 173 3284 0.01 
Methylamphetamine 16 212 0.02 
Cannabis 1109 2420 10 125 0.10 
Ketamine 103 266 941 0.10 
Mephedrone 30 629 0.004 
Anabolic steroids 35 62 316 0.11 
NPS n/a 127 834 n/a 
SubstanceLast monthLast yearEverLast month/Ever
Powder cocaine 331 895 3576 0.09 
Crack cocaine 23 273 0.03 
Ecstasy 172 559 3386 0.05 
LSD 18 134 1755 0.01 
‘Magic mushrooms’ 10 142 2466 0.004 
Heroin 13 23 215 0.06 
Methadone 19 150 0.03 
Amphetamine 32 173 3284 0.01 
Methylamphetamine 16 212 0.02 
Cannabis 1109 2420 10 125 0.10 
Ketamine 103 266 941 0.10 
Mephedrone 30 629 0.004 
Anabolic steroids 35 62 316 0.11 
NPS n/a 127 834 n/a 

Table 1.2 shows deaths in 2020 in England and Wales associated with specific substances, where those substance were mentioned on the death certificate.3  Some of these deaths involved more than one substance. These data include all substances, but two-thirds involved ‘drug misuse’ which is defined as deaths associated with drug abuse, drug-dependence or those that involved a controlled drug (i.e., listed in the MDAct). Figure 1.2 shows the trend in drug-associated deaths in England and Wales for the period 2001 to 2020. In 2020, heroin and morphine accounted for around 30%, and all opiates/opioids combined accounted for nearly 60%. The total number of deaths in 2020 (4561) was the highest number since recording started in 1993 and represents a rate of 79.5 deaths per million people. Males accounted for two-thirds of those deaths. Long delays can occur in recording some deaths; the data show deaths recorded in the year stated rather than occurring in that year. In 2020, drug-associated deaths in Scotland5  reached an all-time high (1339 cases). On a per capita basis, this is over three times the rate in England and Wales. It also the highest rate in Europe although there are some differences in the definition of drug-related deaths used by the Scottish Records Office, the ONS and the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA).

Table 1.2

Deaths in 2020 in England and Wales associated with specific substances

Substance(s) (opiates/opioids)Number of deathsSubstance(s) (others)Number of deaths
Heroin and morphine 1337 Cocaine 777 
Methadone 516 Amphetamine 99 
Tramadol 203 Ecstasy/MDMA 82 
Codeinea 212 Cannabis 36 
Dihydrocodeinea 96 NPS 137 
Oxycodone 102 Benzodiazepines 476 
Fentanyl 57 Zopiclone/Zolpidem 146 
Fentanyl analogues Pregabalin 344 
Buprenorphine 43 Gabapentin 118 
Unspecified opiate 150 Barbiturates 26 
Substance(s) (opiates/opioids)Number of deathsSubstance(s) (others)Number of deaths
Heroin and morphine 1337 Cocaine 777 
Methadone 516 Amphetamine 99 
Tramadol 203 Ecstasy/MDMA 82 
Codeinea 212 Cannabis 36 
Dihydrocodeinea 96 NPS 137 
Oxycodone 102 Benzodiazepines 476 
Fentanyl 57 Zopiclone/Zolpidem 146 
Fentanyl analogues Pregabalin 344 
Buprenorphine 43 Gabapentin 118 
Unspecified opiate 150 Barbiturates 26 
a

Codeine and dihydrocodeine deaths exclude compound formulations.

Figure 1.2

Drug-associated deaths in England and Wales (2001–2020).

Figure 1.2

Drug-associated deaths in England and Wales (2001–2020).

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Table 1.3 lists the number of drug seizures by Police in England and Wales in 2018/19.6  The data exclude those made by the Border Force. A large proportion of those arrested for drugs offences are drug users, rather than suppliers, manufacturers, or importers, and most of those are for the offence of possession. Cannabis in its various forms represented 74% of all seizures. The trend in police drug seizures since 2006/07 is set out in Figure 1.3.

Table 1.3

Drug seizures by Police in England and Wales in 2018/19. The classification of each substance (A, B or C) under the MDAct is shown

SubstanceNumber of seizuresSubstanceNumber of seizures
Cocaine (A) 16 653 Amphetamine (B) 3456 
Crack cocaine (A) 6556 Barbiturates (B) 15 
Ecstasy (A) 2687 Ketamine (B) 862 
Heroin (A) 8338 Mephedrone (B) 58 
LSD (A) 166 Anabolic steroids (C) 463 
Methadone (A) 407 Benzodiazepines (C) 2249 
SubstanceNumber of seizuresSubstanceNumber of seizures
Cocaine (A) 16 653 Amphetamine (B) 3456 
Crack cocaine (A) 6556 Barbiturates (B) 15 
Ecstasy (A) 2687 Ketamine (B) 862 
Heroin (A) 8338 Mephedrone (B) 58 
LSD (A) 166 Anabolic steroids (C) 463 
Methadone (A) 407 Benzodiazepines (C) 2249 
Figure 1.3

Police drug seizures in England and Wales in the period 2006/07 to 2018/19. Class A = dark grey bars; Class B = hatched bars; Class A = black bars.

Figure 1.3

Police drug seizures in England and Wales in the period 2006/07 to 2018/19. Class A = dark grey bars; Class B = hatched bars; Class A = black bars.

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