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Chemical Biology
The Chemical Biology of Carbon
By
Christopher T Walsh
Christopher T Walsh
Stanford University, USA
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Hardback ISBN:
978-1-83916-802-4
PDF ISBN:
978-1-83916-950-2
EPUB ISBN:
978-1-83916-951-9
Special Collection:
2023 ebook collection
Series:
Chemical Biology
No. of Pages:
564
Publication date:
05 Apr 2023
Book Chapter
Chapter 8: Heterocycles: I
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Published:05 Apr 2023
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Special Collection: 2023 ebook collectionSeries: Chemical Biology
Citation
2023. "Heterocycles: I", The Chemical Biology of Carbon, Christopher T Walsh
Download citation file:
We argue that both oxygen-containing and nitrogen-containing heterocyclic ring metabolites are central in metabolic pathways. This chapter examines common C–O heterocycles including hemiacetals, lactones, pyrones, flavanones, and ethers. It also takes up key nitrogen heterocycles including pyrroles, imidazoles, lactams, and indole in the side chain of tryptophan. Biosynthetic logic and key reactivity patterns in terms of nucleophilic and electrophilic groups are identified.
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