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Among the different actions that can be performed with molecules in solution, separations are crucial for the analysis of chemical compounds. At a larger scale, separations can also be used for purification, but this is less relevant at the chip scale. For the separations of different compounds, the most common techniques in use are chromatography and electrophoresis. In this chapter, the use of chromatography and electrophoresis in microfluidics is introduced and their development into industrial implementation is discussed.

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