Enantioselective Cobalt-catalysed [2+1] Cycloadditions

The first chapter of the book deals with enantioselective cobalt-catalysed [2+1] cycloadditions. The first section of this chapter collects together and describes enantioselective cyclopropanation reactions, while the second part of the section deals with aziridination and epoxidation reactions. Concerning cyclopropanations, excellent enantioselectivities have been described using predominantly two types of chiral cobalt complexes, based on salen and porphyrin chiral ligands. In the area of aziridinations, important results have also been described using porphyrin cobalt chiral catalysts, while only rare examples of epoxidations have been developed so far.