In Situ Analysis of Cellular Functional Molecules
Chapter 7: Real-time Monitoring of Intracellular Reactive Oxygen Species
Published:14 Jan 2020
Special Collection: 2020 ebook collectionSeries: Detection Science
2020. "Real-time Monitoring of Intracellular Reactive Oxygen Species", In Situ Analysis of Cellular Functional Molecules, Huangxian Ju, Bo Tang, Lin Ding
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Reactive oxygen species (ROS) are generated and exploited to regulate many physiological processes, but over-production of ROS may cause or accelerate a diverse array of pathological conditions. To understand precisely how ROS play their biological roles, well-established fluorescence imaging approaches have been successfully used to monitor ROS in living cells. This chapter summarizes recent progress in the design and synthesis of various fluorescent probes for the fluorescence imaging of cellular ROS, including superoxide anion, hydrogen peroxide, hydroxyl radical, lipid peroxy radical, HClO, HOBr, 1O2 and O3.