Skip to Main Content
Skip Nav Destination

One of the strategies for controlling cellular levels of the free amino acid cysteine and its nucleophilic, potentially toxic thiolate anion is enzymatic oxygenation. The three possible S-oxidation states are monooxygenated sulfenate, dioxygenated sulfinate and trioxygenated sulfonate. The end point metabolite from S-oxygenation is the decarboxylated sulfonate taurine. The three oxygens are introduced by two enzymes, the first using both oxygen atoms from a molecule of O2, the third being obtained from water. Taurine accumulates as an osmolyte in some tissues and is a conjugation moiety in gastrointestinal retrieval of bile acids such as taurocholic acid.

You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Don't already have an account? Register
Close Modal

or Create an Account

Close Modal
Close Modal