Main post-translational modifications of ribosomal peptides grouped into side chain and main chain modifications. One example is given for each modification.
| Modification . | Example . | Reference . |
|---|---|---|
| Side chain | ||
| Lanthionine formation | Microbisporicine | 27 |
| Oxazoline/Thiazoline formation | Bottromycin | 28 |
| Prenylation | ComX | 29 |
| Disulfide bonding | Enterocin A | 30 |
| β-Hydroxylation | Microbisporicine | 27 |
| Halogenation | Microbisporicine | 27 |
| Alkylation | Bottromycin | 28 |
| Main chain | ||
| Proteolysis | ||
| Macrocyclisation | SubtilosinA | 31 |
| Formylation | LacticinQ | 32 |
| Modification . | Example . | Reference . |
|---|---|---|
| Side chain | ||
| Lanthionine formation | Microbisporicine | 27 |
| Oxazoline/Thiazoline formation | Bottromycin | 28 |
| Prenylation | ComX | 29 |
| Disulfide bonding | Enterocin A | 30 |
| β-Hydroxylation | Microbisporicine | 27 |
| Halogenation | Microbisporicine | 27 |
| Alkylation | Bottromycin | 28 |
| Main chain | ||
| Proteolysis | ||
| Macrocyclisation | SubtilosinA | 31 |
| Formylation | LacticinQ | 32 |