(a) Schematic illustration of TAT-RGD modified copper sulfide nanoparticle formation. In vivo PTT of modified copper sulfide nanoparticles in mice via intravenous injection. (b) Photographs of tumor-bearing mice subjected to different treatments. (c–d) Time-dependent tumor growth rate and body weight. (e) H&E staining and TUNEL staining of the HeLa tumor. Reproduced from ref. 155 with permission from American Chemical Society, Copyright 2018.