XR-seq data from E. coli (left) and human cell lines (right) showing repair patterns in wild type cells (WT, NHF1), transcription-coupled mutants (mfd-, CS-B), mammalian global repair mutants (XP-C), and E. coli cells that can't release repair proteins following an excision repair cycle (Uvrd−). Reproduced from ref. 22 with permission from The American Society for Biochemistry and Molecular Biology, Copyright 2017.